Malaria

Sel getih abang sing kainfèksi déning P.vivax

Malaria iku sajinis lelara nular sing ngakibataké watara 350-500 yuta wong kainfèksi lan punjul 1 yuta mati saben taun, mligi ing laladan tropis lan ing Afrika.

Kanggo panemuan ngenani jalaran malaria, siji dhokter militèr Prancis Charles Louis Alphonse Laveran dianugerahi Bebungah Nobel kanggo Fisiologi lan Medis ing taun 1907.

Sebab lan tandha-tandha

Malaria disebabaké déning parasit protozoa. Plasmodium (salah siji Apicomplexa) lan panularan vèktor kanggo parasit malaria manungsa ya iku lemut Anopheles. Rupa saka Plasmodium falciparum saka parasit iki tanggung jawab marang 80% kasus lan 90% pepati.

Tandha-tandha malaria kalebu demam, nggreges, arthralgia (lara sendhi), muntah-muntah, anemia, lan kejang.

Pangobatan

Pangobatan malaria gumantung marang jinis parasit lan résistènsi parasit marang klorokuin.

Kanggo siji serangan malaria falciparum akut kanthi parasit sing résisten marang klorokuin, bisa diwènèhi kuinin utawa kuinidin kanthi intravena. Sajeroning jinis malaria liyané arang kadadéan résistènsi marang klorokuin, amarga saka iku racaké diwènèhi klorokuin lan primakuin.

Prinsip pananganan malaria kanthi umum ya iku yèn tanpa komplikasi diwènèhi peroral artesunat kombinasi karo amodiakuin (artesdiakuin) utawa coartem utawa duo-cotexcin, déné malaria kanthi komplikasi diwènèhi artesunat 2,4 mg/kgbb ing jam ka 0 - 12 - 24 - 72 lan saterusé nganti pasien bisa diterapi kanthi oral utawa digunakaké artemeter 3,2 mg/kgbb diterusaké nganggo 1,6 mg/kgbb.

Réferènsi

• Ito J, Ghosh A, Moreira LA, Wimmer EA, Jacobs-Lorena M. Transgenic anopheline mosquitoes impaired in transmission of a malaria parasite. Nature 2002;417:387-8. PMID 12024215

Pranala njaba

• WHO site on malaria
• CDC site on malaria
• Medline Plus site on malaria
• LookSmart - Malaria directory category
• Open Directory Project - Malaria Archived 2005-09-11 at the Wayback Machine. directory category
• Yahoo! - Malaria Archived 2006-01-17 at the Wayback Machine. directory category
• Medicastore malaria Archived 2011-08-20 at the Wayback Machine. directory category

Vaksin lan riset liyané

• Malaria Vaccine Initiative
• Malaria Atlas Project Archived 2015-03-30 at the Wayback Machine.
• Wellcome Trust against Malaria Archived 2006-06-13 at the Wayback Machine.
• New Scientist - New Malaria Vaccine Raises High Hopes 15 October 2004
• BBC - Hopes of Malaria Vaccine by 2010 15 October 2004
• Malaria. The UNICEF-UNDP-World Bank-WHO Special Programme for Research and Training in Tropical Diseases
• story of the discovery of the vector of the malarial parasite Archived 2006-06-14 at the Wayback Machine.
• History of discoveries in malaria Archived 2014-06-19 at the Wayback Machine.
• History of Malaria in Spain
• BBC - Science shows how malaria hides 8 April 2005

DDT

• The DDT Ban Myth

Animasi, gambar, lan foto

• Burden of Malaria, BBC pictures relating to malaria in northern Uganda
• Malaria: Cooperation among Parasite, Vector, and Host (Animation)